DNMT3B polyclonal antibody
产品名称： DNMT3B polyclonal antibody
英文名称： DNMT3B polyclonal antibody
产品编号： PAB24969
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of DNMT3B.
- Immunogen:
- A synthetic peptide corresponding to DNMT3B.
- Host:
- Rabbit
- Theoretical MW (kDa):
- 96
- Reactivity:
- Human
- Specificity:
- DNMT3B polyclonal antibody detects endogenous levels of DNMT3B protein.
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 1 mg/mL
- Storage Buffer:
- In PBS, pH 7.2 (0.05% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of HT-29 cell lysate with DNMT3B polyclonal antibody (Cat # PAB24969).
- Entrez GeneID:
- 1789
- Gene Name:
- DNMT3B
- Gene Alias:
- ICF,M.HsaIIIB
- Gene Description:
- DNA (cytosine-5-)-methyltransferase 3 beta
- Gene Ontology:
- Hyperlink
- Gene Summary:
- CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Six alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined. [provided by RefSeq
- Other Designations:
- DNA MTase HsaIIIB,DNA cytosine-5 methyltransferase 3 beta,DNA methyltransferase HsaIIIB
- Gene Pathway
- Related Disease
- Acute Disease
- Adenocarcinoma
- Adenomatous Polyps
- Alzheimer disease
- Arsenic Poisoning
- Arthritis, Rheumatoid
- Breast cancer
- Breast Neoplasms
- Carcinoma
- Carcinoma, Hepatocellular
- Carcinoma, Squamous Cell
- Chronic Disease
- Colon cancer
- Colonic Neoplasms
- Colonic Polyps
- Colorectal Neoplasms
- Colorectal Neoplasms, Hereditary Nonpolyposis
- Cues
- Disease Progression