OTUD5 polyclonal antibody
产品名称： OTUD5 polyclonal antibody
英文名称： OTUD5 polyclonal antibody
产品编号： PAB16553
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of OTUD5.
- Immunogen:
- A synthetic peptide corresponding to C-terminus 13 amino acids of human OTUD5.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.02% sodium azide)
- Storage Instruction:
- Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- DUBA: a deubiquitinase that regulates type I interferon production.
Kayagaki N, Phung Q, Chan S, Chaudhari R, Quan C, O'Rourke KM, Eby M, Pietras E, Cheng G, Bazan JF, Zhang Z, Arnott D, Dixit VM.Science. 2007 Dec 7;318(5856):1628-32. Epub 2007 Nov 8.
- 2.
- Chemistry-based functional proteomics reveals novel members of the deubiquitinating enzyme family.
Borodovsky A, Ovaa H, Kolli N, Gan-Erdene T, Wilkinson KD, Ploegh HL, Kessler BM.Chem Biol. 2002 Oct;9(10):1149-59.
- Applications
- Western Blot (Tissue lysate)
- Western blot analysis of OTUD5 in human kidney lysate with OTUD5 polyclonal antibody (Cat # PAB16553) at (Lane 1) 1 and (Lane 2) 2 ug/mL .
- Entrez GeneID:
- 55593
- Protein Accession#:
- EAW50723
- Gene Name:
- OTUD5
- Gene Alias:
- DKFZp761A052,DUBA,MGC104871
- Gene Description:
- OTU domain containing 5
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq
- Other Designations:
- OTTHUMP00000025821,deubiquinating enzyme A