FITC标记的红细胞糖苷α1抗体
产品名称： FITC标记的红细胞糖苷α1抗体
英文名称： Anti-GBGT1/FITC
产品编号： HZ-13301R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-GBGT1/FITC Conjugated antibody
FITC标记的红细胞糖苷α1抗体
| 英文名称 | Anti-GBGT1/FITC |
| 中文名称 | FITC标记的红细胞糖苷α1抗体 |
| 别 名 | 3-N-acetylgalactosaminyltransferase 1; A3GALNT; EC=2.4.1.-; Forssman glycolipid synthase-like protein; Forssman glycolipid synthetase (FS); Forssman synthetase; FS; GBGT1; GBGT1_HUMAN; Globoside alpha-1; globoside alpha-1,3-N-acetylgalactosaminyltransferase 1; glycolipid synthase-like protein; RP11-326L24.6; UNQ2513; UNQ2513/PRO6002. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 新陈代谢 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 40kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GBGT1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: GBGT1 is a 347 amino acid single-pass type II membrane protein that belongs to the glycosyltransferase 6 family. Localizing to the golgi apparatus membrane, GBGT1 is widely expressed, with high levels found in placenta, ovary and peripheral blood leukocyte, and lower levels expressed in liver, thymus and testis. GBGT1 utilizes manganese as a cofactor, and assists in the addition of N-acetylgalactosamine (GalNAc) in alpha-1,3-linkage to various substrates, resulting in the formation of glycolipids. Glycolipids are present in most eukaryotic cells and may assist in the adherence of certain pathogens. Existing as two alternatively spliced isoforms, the gene encoding GBGT1 maps to human chromosome 9q34.2 and mouse chromosome 2 A3. Function: Catalyzes the formation of some glycolipid via the addition of N-acetylgalactosamine (GalNAc) in alpha-1,3-linkage to some substrate. Glycolipids probably serve for adherence of some pathogens. Subcellular Location: Golgi apparatus membrane. Tissue Specificity: Widely expressed. Expressed at higher level in placenta, ovary and peripheral blood leukocyte, whereas it is weakly expressed in liver, thymus, and testis. Similarity: Belongs to the glycosyltransferase 6 family. Database links: UniProtKB/Swiss-Prot: Q8N5D6.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
GBGT1是属于糖基转移酶6家族的347氨基酸单程II型膜蛋白。GBGT1定位于高尔基体膜，广泛表达，在胎盘、卵巢和外周血白细胞中高水平表达，在肝脏、胸腺和睾丸中低水平表达。GBGT1利用锰作为辅因子，并协助将N-乙酰半乳糖胺(GalNAc)以α-1，3-键加到各种底物上，从而形成糖脂。糖脂存在于大多数真核细胞中，并有助于某些病原体的粘附。作为两个交替剪接的亚型存在，编码gbgt1的基因映射到人类染色体9q34.2和小鼠染色体2 a3。