TRPC6 polyclonal antibody
产品名称： TRPC6 polyclonal antibody
英文名称： TRPC6 polyclonal antibody
产品编号： PAB7504
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of TRPC6.
- Immunogen:
- A synthetic peptide corresponding to human TRPC6.
- Sequence:
- C-EKLSMEPNQEETN
- Host:
- Goat
- Theoretical MW (kDa):
- 106
- Reactivity:
- Mouse
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:2000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis.
Winn MP, Conlon PJ, Lynn KL, Farrington MK, Creazzo T, Hawkins AF, Daskalakis N, Kwan SY, Ebersviller S, Burchette JL, Pericak-Vance MA, Howell DN, Vance JM, Rosenberg PB.Science. 2005 Jun 17;308(5729):1801-4. Epub 2005 May 5.
- Application Image
- ELISA
- Flow Cytometry
- Entrez GeneID:
- 7225
- Protein Accession#:
- NP_004612.2
- Gene Name:
- TRPC6
- Gene Alias:
- FLJ11098,FLJ14863,FSGS2,TRP6
- Gene Description:
- transient receptor potential cation channel, subfamily C, member 6
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). [provided by RefSeq
- Other Designations:
- transient receptor potential channel 6