上海中乔新舟生物科技有限公司是美国Sciencell公司中国一级代理：

         美国ScienCell研究实验室（www.sciencellonline.com）成立于1999年，公司总部位于美国加州的圣地亚哥。主要致力于实验室科研用原代细胞、原代细胞专用培养基、原代细胞无血清培养基、干细胞、干细胞培养基、干细胞无血清培养基的研究和开发，在全球拥有众多客户。在国内销售15年来，很多老师应用其产品发表了高质量的SCI文章，且有着极高的文献引用率。凭借着严格的质控和优秀的产品品质，深受广大科研工作者的信赖。
         ScienCell研究实验室生产的原代细胞、原代细胞专用培养基都经过了严格的质量控制，细胞纯度可达98％。其中包括21种人体正常细胞系统，90多种不同细胞类型。大多数细胞在全球唯有ScienCell实验室能够成功分离，产品质量过硬。确保了实验结果的重复性和连贯性。

请登录Sciencell公司官方网站（www.zqxzbio.com或www.sciencell-sh.com）以确保购买正规公司产品。

产品：大鼠主动脉平滑肌细胞

 货号：R6110

Description

Smooth muscle cell (SMC) is the cellular substate of most significant arterial disease [1]. The increased growth potential of vascular SMC represents one of the crucial anomalies responsible for the development of essential vascular diseases. New studies demonstrate that SMC express calcium channels [2] and the expression of ICAM-1 and VCAM-1 on SMC may contribute to the inflammatory reaction in the vascular wall and may actively be involved in the progression and stability of vascular disease [3]. Culture of vascular SMC as a model of vascular research played a critical role and continues providing information in the pharmacology and the therapy of vascular diseases.

RASMC from ScienCell Research Laboratories are isolated rat aorta. RASMC are cryopreserved after purification and delivered frozen. Each vial contains >5 x 105 cells in 1 ml volume. RASMC are characterized by immunofluorescent method with antibodies to a-smooth muscle actin and desmin. RASMC are negative for mycoplasma, bacteria, yeast and fungi. RASMC are guaranteed to further expand for 15 population doublings at the condition provided by ScienCell Research Laboratories.

 Recommended Medium

It is recommended to use Smooth Muscle Cell Medium (SMCM, Cat. No. 1101) for the culturing of RASMC in vitro.

Product Use

RASMC are for research use only. It is not approved for human or animal use, or for application in in vitro diagnostic procedures.

Storage

Directly and immediately transfer cells from dry ice to liquid nitrogen upon receiving and keep the cells in liquid nitrogen until cell culture needed for experiments.

Shipping

Dry ice.

Reference

[1] Schwartz, S. M., Campbell, G. R., Campbell, J. H. (1986) Replication of smooth muscle cells in vascular disease. Circ. Res. 58:427-444.
[2] Fan, Q. I., Vanderpool, K., Marsh, J. D. (2002) A 27 bp cis-acting sequence is essential for L-type calcium channel alpha(1C) subunit expression in vascular smooth muscle cells. Biochim Biophys Acta. 1577:401-11.
[3] Braun, M., Pietsch, P., Schror, K., Baumann, G., Felix, S. B. (1999) Cellular adhesion molecules on vascular smooth muscle cells. Cardiovasc. Res. 41:395-401.