APP polyclonal antibody
产品名称： APP polyclonal antibody
英文名称： APP polyclonal antibody
产品编号： PAB25101
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of APP.
- Immunogen:
- A synthetic peptide corresponding to APP.
- Host:
- Rabbit
- Theoretical MW (kDa):
- 51
- Reactivity:
- Human
- Specificity:
- APP polyclonal antibody detects endogenous levels of APP protein.
- Form:
- Liquid
- Purification:
- Affinity purification
- Concentration:
- 1 mg/mL
- Storage Buffer:
- In PBS, pH 7.2 (0.05% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 351
- Gene Name:
- APP
- Gene Alias:
- AAA,ABETA,ABPP,AD1,APPI,CTFgamma,CVAP,PN2
- Gene Description:
- amyloid beta (A4) precursor protein
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- A4 amyloid protein,amyloid beta A4 protein,amyloid-beta protein,beta-amyloid peptide,cerebral vascular amyloid peptide,peptidase nexin-II,protease nexin-II
- Interactome
- Gene Pathway
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Amyloidosis, Familial
- Cardiovascular Diseases
- Celiac Disease
- Cerebral Hemorrhage
- Cerebrovascular Disorders
- Cognition
- Cognition Disorders
- Dementia
- Diabetes Mellitus, Type 2
- Disease Progression
- Disease Susceptibility
- Down Syndrome
- Edema
- Genetic Predisposition to Disease
- Headache
- Macular Degeneration
- Mental Status Schedule