磷酸化磷酯酶Cβ3抗体
产品名称： 磷酸化磷酯酶Cβ3抗体
英文名称： Phospho-PLC beta3 (Ser1105)
产品编号： hz-3341R
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=1μg /Test IF=1:100-500
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Rabbit Anti-Phospho-PLC beta3 (Ser1105) antibody
| 产品编号 | hz-3341R |
| 英文名称 | Phospho-PLC beta3 (Ser1105) |
| 中文名称 | 磷酸化磷酯酶Cβ3抗体 |
| 别 名 | Phospholipase C beta 3; Phospholipase C beta 3 (phosphatidylinositol specific); PLC beta 3; PLCB3 antibody 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase beta 3; Phosphoinositide phospholipase C; PLCB3_HUMAN. |
| 产品类型 | 磷酸化抗体 |
| 研究领域 | 肿瘤 免疫学 信号转导 转录调节因子 激酶和磷酸酶 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, |
| 产品应用 | WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 Flow-Cyt=1μg /Test IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 136kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthesised phosphopeptide derived from human PLC beta3 around the phosphorylation site of Ser1105:N(p-S)ISE |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | background: Phospholipase C is a key enzyme in phosphatidylinositol (PIP2) metabolism and lipid signaling pathways. The Phospholipase C family consists of 13 isozymes split between six subfamilies. Phospholipase C beta is activated by G protein subunits. Function: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. Subunit: Interacts with SHANK2. Interacts with LPAR2. Subcellular Location: Membrane; Peripheral membrane protein. Similarity: Contains 1 C2 domain. Contains 1 PI-PLC X-box domain. Contains 1 PI-PLC Y-box domain. Gene ID: 5331 Database links: Entrez Gene: 5331 Human Entrez Gene: 18797 Mouse Entrez Gene: 29322 Rat Omim: 600230 Human SwissProt: Q01970 Human SwissProt: P51432 Mouse SwissProt: Q99JE6 Rat Unigene: 523761 Human Unigene: 591953 Human Unigene: 273204 Mouse Unigene: 16983 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品图片 |
 Blank control(blue): RAJI(fixed with 2% paraformaldehyde (10 min)).
Primary Antibody:Rabbit Anti-Phospho-PLC beta3 (Ser1105) antibody(bs-3341R), Dilution: 1μg in 100 μL 1X PBS containing 0.5% BSA; Isotype Control Antibody: Rabbit IgG(orange) ,used under the same conditions ); Secondary Antibody: Goat anti-rabbit IgG-PE(white blue), Dilution: 1:200 in 1 X PBS containing 0.5% BSA. |