FITC标记的黑色素瘤相关抗原B6抗体
产品名称： FITC标记的黑色素瘤相关抗原B6抗体
英文名称： Anti-MAGEB6/FITC
产品编号： HZ-
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-MAGEB6/FITC Conjugated antibody
FITC标记的黑色素瘤相关抗原B6抗体
| 英文名称 | Anti-MAGEB6/FITC |
| 中文名称 | FITC标记的黑色素瘤相关抗原B6抗体 |
| 别 名 | Cancer/testis antigen 3.4; CT3.4; MAGEB6 antigen; Melanoma associated antigen B6; MAGB6_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞类型标志物 肿瘤细胞生物标志物 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 44kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MAGEB6 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. The MAGE genes were initially isolated from different type of tumors, and based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGE genes encode for tumor-rejection antigens and are expressed in tumors of different histologic types, but not in normal tissues, with the exception of testis and placenta. Although a large number of MAGE genes have now been identified and extensively studied in tumors of various origin, their function in normal cells remains unknown. MAGE-B6 is expressed in testis and tumors of various histological origins but has not been shown to be expressed in other normal tissues. Tissue Specificity: Expressed in testis. Not expressed in other normal tissues, but is expressed in tumors of different histological origins. Similarity: Contains 1 MAGE domain. Database links: Entrez Gene: 158809 Human Omim: 300467 Human SwissProt: Q8N7X4 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
黑色素瘤相关抗原（MAGE）家族由许多由细胞毒性T淋巴细胞识别的抗原组成。MAGE基因最初是从不同类型的肿瘤中分离出来的，并且基于它们在组织中的特异性肿瘤特异性表达，它们已经被用作癌症免疫治疗的靶点。MAGE基因编码肿瘤排斥抗原，并在不同组织学类型的肿瘤中表达，而在正常组织中则不表达，除睾丸和胎盘外。虽然许多MAGE基因已被鉴定并广泛研究在各种来源的肿瘤中，但它们在正常细胞中的功能尚不清楚。MAGE-B6在不同组织学来源的睾丸和肿瘤中表达，但未在其他正常组织中表达。