ELK3,血清反应因子辅助蛋白SAP2抗体

产品编号HZ-14565R
英文名称ELK3
中文名称血清反应因子辅助蛋白SAP2抗体
别 名ELK3; ELK3, ETS domain protein (SRF accessory protein 2); ELK3_HUMAN; ERP; ETS domain protein; ETS domain-containing protein Elk-3; ETS related protein ERP; ETS related protein NET; ETS-related protein ERP; ETS-related protein NET; NET; SAP 2; SAP-2; SAP2; Serum response factor accessory protein 2; SRF accessory protein 2.
说 明 书0.1ml 0.2ml
研究领域细胞生物 免疫学 表观遗传学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit,
ELK3,血清反应因子辅助蛋白SAP2抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量44kDa
细胞定位细胞核
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human ELK3
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
ELK3,血清反应因子辅助蛋白SAP2抗体PubMedPubMed
产品介绍background:
The protein encoded by this gene is a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present. [provided by RefSeq, Jul 2008]

Function:
May be a negative regulator of transcription, but can activate transcription when coexpressed with Ras, Src or Mos. Forms a ternary complex with the serum response factor and the ETS and SRF motifs of the Fos serum response element.

Subunit:
Interacts with CTBP1.

Subcellular Location:
Nucleus.

ELK3,血清反应因子辅助蛋白SAP2抗体Similarity:
Belongs to the ETS family.
Contains 1 ETS DNA-binding domain.

Gene ID:
2004

Database links:
Entrez Gene: 2004 Human
Entrez Gene: 417919 Chicken
Entrez Gene: 541125 Cow
Entrez Gene: 482613 Dog
Entrez Gene: 13713 Mouse
Entrez Gene: 362871 Rat
Omim: 600247 Human
SwissProt: P41970 Human
SwissProt: P41971 Mouse
Unigene: 46523 Human
Unigene: 4454 Mouse
Unigene: 196088 Rat

ELK3,血清反应因子辅助蛋白SAP2抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品图片

Protein: mouse lung lysate; Primary: rabbit Anti-ELK3 (bs-14565R) at 1:300;  Secondary: HRP conjugated Goat-Anti-rabbit IgG(bs-0295G-HRP) at 1: 5000;  Predicted band size: 44 kD Observed band size: 44 kD Protein: mouse spleen lysate; Primary: rabbit Anti-ELK3 (HZ-14565R) at 1:300;  Secondary: HRP conjugated Goat-Anti-rabbit IgG(HZ-0295G-HRP) at 1: 5000;  Predicted band size: 44 kD Observed band size: 44 kD