FITC标记的原钙粘蛋白γA2抗体
产品名称： FITC标记的原钙粘蛋白γA2抗体
英文名称： Anti-PCDHGA2/FITC
产品编号： HZ-11145R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-PCDHGA2/FITC Conjugated antibody
FITC标记的原钙粘蛋白γA2抗体
| 产品编号 | bs-11145R-FITC |
| 英文名称 | Anti-PCDHGA2/FITC |
| 中文名称 | FITC标记的原钙粘蛋白γA2抗体 |
| 别 名 | PCDHG-A2; PCDH gamma A2; Protocadherin gamma A2; Protocadherin gamma subfamily A 2; PCDG2_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 信号转导 细胞粘附分子 细胞骨架 细胞膜蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 98kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PCDHGA2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHGA2 (Protocadherin gamma A2) is a 932 amino acid protein that is one of 22 proteins encoded by the protocadherin gamma cluster. The protocadherein gamma cluster consists of three subfamilies (A, B and C) and PCDHGA2 is a member of the gamma subfamily A. PCDHGA2 contains six cadherin motifs, and characteristic of gamma protocadherins, PCDHGA2 is a type I transmembrane receptor expressed in the central nervous system and localizes to synapses. Members of the gamma cluster of protocadherins are essential for neuronal survival. Function: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain. Subcellular Location: Cell membrane; Single-pass type I membrane protein. Similarity: Contains 6 cadherin domains. Database links: Entrez Gene: 56113 Human Entrez Gene: 93710 Mouse UniProtKB/Swiss-Prot: Q9Y5H1.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
原粘蛋白是一大类钙黏蛋白样细胞粘附蛋白，参与脑内神经元连接的建立和维持。共有三个原螯合蛋白基因簇，分别为α、β和γ，它们均含有多个排列整齐的基因。PCDHGA2（原粘蛋白γ-A2）是由原粘蛋白γ簇编码的22种蛋白质中的932种氨基酸之一。原代Gamma簇由三个亚科（A、B和C）组成，PCDHGA2是γ亚家族的成员。PCDHGA2含有六个钙粘素基序，而γ-原黏附蛋白的特征是PCDHGA2是在中枢神经系统和基因座中表达的I型跨膜受体。利兹到突触。原核粘附素簇的成员对神经元存活至关重要。