FITC标记的GRXCR1蛋白抗体
产品名称： FITC标记的GRXCR1蛋白抗体
英文名称： Anti-GRXCR1/FITC
产品编号： HZ-16329R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749 点击查看
- 传真 : 点击查看
- 邮箱 : www.shzbio.net
- 二维码 : 点击查看
Rabbit Anti-GRXCR1/FITC Conjugated antibody
FITC标记的GRXCR1蛋白抗体
| 英文名称 | Anti-GRXCR1/FITC |
| 中文名称 | FITC标记的GRXCR1蛋白抗体 |
| 别 名 | DFNB25; Glutaredoxin domain-containing cysteine-rich protein 1; Glutaredoxin, cysteine rich 1; GRCR1_HUMAN; Grxcr1. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 神经生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Cow, Horse, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 32kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GRXCR1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene is one of 60 loci associated with autosomal-recessive nonsyndromic hearing impairment. This gene encodes a protein which contains GRX-like domains; these domains play a role in the S-glutathionylation of proteins and may be involved in actin organization in hair cells. [provided by RefSeq, Sep 2010] Function: Expressed at low levels in adult lung, brain and duodenum with moderate levels in testis. Highly expressed in fetal cochlea. Subcellular Location: Cell projection; stereocilium. Cell projection > microvillus. Cell projection; kinocilium. In the inner ear, localized to stereocilia, apical microvilli of sensory cells and kinocilia. DISEASE: Defects in GRXCR1 are the cause of deafness autosomal recessive type 25 (DFNB25) [MIM:613285]. DFNB25 is characterized by moderate to severe or profound hearing loss which is progressive in some individuals but not in others. Speech development is impaired in some but not all affected individuals and vestibular dysfunction is observed in some affected individuals. Similarity: Belongs to the GRXCR1 family. Contains 1 glutaredoxin domain. Database links: Entrez Gene: 389207 Human Omim: 613283 Human SwissProt: A8MXD5 Human Unigene: 162559 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因是常染色体隐性遗传非综合征性听力损害的60个位点之一。该基因编码的蛋白质，其中包含GRX样结构域；这些域在蛋白质S-谷胱甘肽发挥作用，可能参与毛细胞肌动蛋白的组织。[ RefSeq，SEP 2010提供]