DPM2 polyclonal antibody
产品名称： DPM2 polyclonal antibody
英文名称： DPM2 polyclonal antibody
产品编号： PAB17035
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of DPM2.
- Immunogen:
- A synthetic peptide corresponding to human DPM2.
- Sequence:
- C-SYVMLKTKRVTKKAQ
- Host:
- Goat
- Theoretical MW (kDa):
- 9.31
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:8000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Initial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG-P and is regulated by DPM2.
Watanabe R, Murakami Y, Marmor MD, Inoue N, Maeda Y, Hino J, Kangawa K, Julius M, Kinoshita T.EMBO J. 2000 Aug 15;19(16):4402-11.
- Application Image
- ELISA
- Entrez GeneID:
- 8818
- Protein Accession#:
- NP_003854.1
- Gene Name:
- DPM2
- Gene Alias:
- FLJ80013,MGC111193,MGC21559
- Gene Description:
- dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
- Omim ID:
- 603564
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by this gene is a hydrophobic protein that contains 2 predicted transmembrane domains and a putative ER localization signal near the C terminus. This protein associates with DPM1 in vivo and is required for the ER localization and stable expression of DPM1 and also enhances the binding of dolichol-phosphate to DPM1. [provided by RefSeq
- Other Designations:
- OTTHUMP00000022224,dolichol phosphate-mannose biosynthesis regulatory protein,dolichol phosphate-mannose synthase 2