Recombinant Rat VEGF Co-regulated Chemokine 1/CXCL17(Rat VCC-1/CXCL17)
产品名称： Recombinant Rat VEGF Co-regulated Chemokine 1/CXCL17(Rat VCC-1/CXCL17)
英文名称： Recombinant Rat VEGF Co-regulated Chemokine 1/CXCL17(Rat VCC-1/CXCL17)
产品编号： 90996ES10
产品价格： 0
产品产地： Yeasen
品牌商标： Yeasen
更新时间： 2023-08-17T13:40:59
使用范围： null
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Product Information
Product Name
Cat#
Size
Price（¥）
Recombinant Rat VEGF Co-regulated Chemokine 1/CXCL17(Rat VCC-1/CXCL17)
90996ES10
10 μg
1855
90996ES60
100 μg
9655
90996ES76
500 μg
25445
Product Description
Dendritic cell and monocyte chemokine-like protein (DMC), also known as VEGF-correlated chemokine-1 (VCC-1), is a secreted molecule with a size and predicted three-dimensional folding pattern similar to that of chemokines CXCL8/IL-8 and CXCL14/BRAK. It has no predicted N-glycosylation sites, so cleavage of a 22 amino acid (aa) signal sequence likely results in a mature mouse DMC molecule of 97 aa and 11 kDa size. DMC is constitutively produced by airway and intestinal epithelium. It induces the chemotaxis of quiescent, but not LPSactivated peripheral blood monocytes and dendritic cells, and also binds these cells specifically.
Product Properties
Synonyms
Dendritic Cell and Monocyte Chemokine-like Protein, DMC
Source
E.coli-derived Rat CXCL17 protein,Ser23-Leu119.
Molecular Weight
Approximately 11.5 kDa
AA Sequence
SPNQEVARHH GDQHQAPRRW LWEGGQECDC KDWSLRVSKR KTTAVLEPPR KQCPCDHVKG SEKKNRRQKH HRKSQRPSRT CQQFLKRCQL ASFTLPL
Tag
None
Physical Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Purity
> 97% by SDS-PAGE and HPLC analyses.
Biological Activity
Fully biologically active when compared to standard. The ED50 as determined by its ability to induce VEGF expression using murine endothelial cells is less than 5.0 μg/ml, corresponding to a specific activity of > 200 IU/mg.
Endotoxin
<0.1 EU/μg of protein as determined by LAL method.
Formulation
Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20°C. Further dilutions should be made in appropriate buffered solutions.
Shipping and Storage
The products are shipped with ice pack and can be stored at -20℃ to -80℃ for 1 year.
Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.
Cautions
1. Avoid repeated freeze-thaw cycles.
2. For your safety and health, please wear lab coats and disposable gloves for operation.
3. For research use only.
HB220511