FITC标记的脑发育同源蛋白2抗体
产品名称: FITC标记的脑发育同源蛋白2抗体
英文名称: Anti-DBX2/FITC
产品编号: HZ-12149R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-DBX2/FITC Conjugated antibody
FITC标记的脑发育同源蛋白2抗体
英文名称 | Anti-DBX2/FITC |
中文名称 | FITC标记的脑发育同源蛋白2抗体 |
别 名 | Dbx 2; developing brain homeobox 2; FLJ16139; hlx3; DBX2_HUMAN. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 发育生物学 神经生物学 信号转导 干细胞 表观遗传学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Horse, Sheep, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 37kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human DBX2 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: DBX2 is a 339 amino acid member of the H2.0 homeobox family. DBX2, which is localized to the nucleus, contains one homeobox DNA-binding domain, a region of 60 amino acids that binds DNA through a helix-turn-helix type of structure. DBX2, which is expressed in the forebrain, midbrain, hindbrain and spinal cord, has been implicated in CNS development.Specifically, DBX2 has been shown to play a role in spinal cord dorsal/ventral patterning, as well as the regionalization of the CNS. DBX2 is also thought to play a role in the production of multiple spinal cord cell types. Subcellular Location: Nuclear Similarity: Belongs to the H2.0 homeobox family. Contains 1 homeobox DNA-binding domain. Database links: Entrez Gene: 440097 Human Entrez Gene: 223843 Mouse Entrez Gene: 541457 Rat SwissProt: Q6ZNG2 Human Unigene: 302764 Human Unigene: 152937 Mouse Unigene: 93216 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application |
DX2是H2.0同源盒家族的339氨基酸成员。DBX2定位于细胞核,包含一个同源盒DNA结合结构域,该结构域由60个氨基酸组成,通过螺旋-旋转-螺旋结构结合DNA。DBX2在前脑、中脑、后脑和脊髓中均有表达,参与中枢神经系统的发育。具体而言,DBX2在脊髓背/腹侧模式以及中枢神经系统的区域化中发挥作用。DX2也被认为在多种脊髓细胞类型的产生中起作用。