DUSP9 polyclonal antibody
产品名称: DUSP9 polyclonal antibody
英文名称: DUSP9 polyclonal antibody
产品编号: PAB2153
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of DUSP9.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human DUSP9.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Genomic organization of two novel genes on human Xq28: compact head to head arrangement of IDH gamma and TRAP delta is conserved in rat and mouse.
Brenner V, Nyakatura G, Rosenthal A, Platzer M.Genomics. 1997 Aug 15;44(1):8-14.
- 2.
- Molecular cloning and functional characterization of a novel mitogen-activated protein kinase phosphatase, MKP-4.
Muda M, Boschert U, Smith A, Antonsson B, Gillieron C, Chabert C, Camps M, Martinou I, Ashworth A, Arkinstall S.J Biol Chem. 1997 Feb 21;272(8):5141-51.
- Applications
- Western Blot (Tissue lysate)
- Western blot analysis of DUSP9 polyclonal antibody (Cat # PAB2153) in mouse kidney tissue lysate (35 ug/lane). DUSP9 (arrow) was detected using the purified Polyclonal antibody (1 : 60 dilution).
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with DUSP9 polyclonal antibody (Cat # PAB2153) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.
This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.
- Entrez GeneID:
- 1852
- Protein Accession#:
- NP_001386;Q99956
- Gene Name:
- DUSP9
- Gene Alias:
- MKP-4,MKP4
- Gene Description:
- dual specificity phosphatase 9
- Omim ID:
- 300134
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases, is expressed only in placenta, kidney, and fetal liver, and is localized to the cytoplasm and nucleus. [provided by RefSeq
- Other Designations:
- OTTHUMP00000025951,OTTHUMP00000025953,map kinase phosphatase 4,serine/threonine specific protein phosphatase
- Interactome
- Gene Pathway
- Related Disease