FITC标记的N-乙酰转移酶8抗体
产品名称: FITC标记的N-乙酰转移酶8抗体
英文名称: Anti-NAT8 + NAT8B/FITC
产品编号: HZ-11591R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-NAT8 + NAT8B/FITC Conjugated antibody
FITC标记的N-乙酰转移酶8抗体
产品编号 | bs-11591R-FITC |
英文名称 | Anti-NAT8 + NAT8B/FITC |
中文名称 | FITC标记的N-乙酰转移酶8抗体 |
别 名 | NAT8+NAT8B; Camello-like protein 1; NAT8; NAT8_HUMAN; Probable N-acetyltransferase 8; Camello like protein 2; Camello-like protein 2; CML2; Hcml2; N acetyltransferase 8B; NAT8B; NAT8B_HUMAN; NAT8BP; Probable N acetyltransferase 8B; Probable N-acetyltransferase 8B. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 肿瘤 细胞生物 发育生物学 信号转导 细胞周期蛋白 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Dog, Horse, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 26kDa |
细胞定位 | 细胞膜 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human NAT8 (141-220aa) |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: NAT8 gene, isolated using the differential display method to detect tissue-specific genes, is specifically expressed in kidney and liver. The encoded protein shows amino acid sequence similarity to N-acetyltransferases. A similar protein in Xenopus affects cell adhesion and gastrulation movements, and may be localized in the secretory pathway. A highly similar paralog is found in a cluster with this gene. [provided by RefSeq, Sep 2008]. NAT8B protein encoded by this gene is highly similar to the N-acetyltransferase 8 (NAT8) gene product, which is a kidney and liver protein with homology to bacterial acetyltransferases involved in drug resistance. This gene is localized on chromosome 2 in the vicinity of the NAT8 gene and may represent a pseudogene of NAT8. This gene contains two polymorphic nonsense mutations that disrupt the active site of the protein. The full-length product of this gene contains a complete acetyltransferase domain and is identical in length to NAT8. [provided by RefSeq, Jul 2008]. Function: Plays a role in regulation of gastrulation. Subcellular Location: Membrane. Tissue Specificity: Expression is restricted to liver and kidney. Similarity: Belongs to the camello family. Contains 1 N-acetyltransferase domain. Database links: Entrez Gene: 9027 Human Entrez Gene: 51471 Human NCBI: NP_057431 Human Omim: 606716 Human Omim: 608190 Human SwissProt: Q9UHE5 Human SwissProt: Q9UHF3 Human Unigene: 14637 Human Unigene: 728429 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application |
NAT8基因在肾脏和肝脏中特异性表达,用差异显示法检测组织特异性基因。编码的蛋白质显示与N-乙酰转移酶的氨基酸序列相似性。爪蟾中类似的蛋白质影响细胞粘附和原肠运动,并可能局限于分泌途径。在这个基因簇中发现了一个高度相似的旁系同源词。