ELP4,ELP4蛋白抗体

产品编号HZ-14574R
英文名称ELP4
中文名称ELP4蛋白抗体
别 名C11orf19; dJ68P15A.1; elongation protein 4 homolog (S. cerevisiae); Elongation protein 4 homolog; Elongator complex protein 4; ELP4; ELP4_HUMAN; FLJ20498; hELP4; PAX6 neighbor gene protein; PAX6NEB; PAXNEB.
说 明 书0.1ml 0.2ml
研究领域细胞生物 神经生物学 信号转导 转录调节因子 表观遗传学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Rabbit,
ELP4,ELP4蛋白抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量47kDa
细胞定位细胞核 细胞浆
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human ELP4
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
ELP4,ELP4蛋白抗体PubMedPubMed
产品介绍background:
This gene encodes a membrane-bound protein which is a member of the ELO family, proteins which participate in the biosynthesis of fatty acids. Consistent with the expression of the encoded protein in photoreceptor cells of the retina, mutations and small deletions in this gene are associated with Stargardt-like macular dystrophy (STGD3) and autosomal dominant Stargardt-like macular dystrophy (ADMD), also referred to as autosomal dominant atrophic macular degeneration. [provided by RefSeq, Jul 2008]

Function:
Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4.

Subcellular Location:
Cytoplasm. Nucleus.

Tissue Specificity:
Widely expressed

ELP4,ELP4蛋白抗体Similarity:
Belongs to the ELP4 family.

Gene ID:
26610

Database links:
Entrez Gene: 26610 Human
Entrez Gene: 77766 Mouse
Entrez Gene: 100514702 Pig
Entrez Gene: 691133 Rat
Entrez Gene: 550331 Zebrafish
Omim: 606985 Human
SwissProt: Q2TBH6 Cow
SwissProt: Q96EB1 Human
SwissProt: Q9ER73 Mouse
SwissProt: Q566Y1 Zebrafish
Unigene: 175534 Human
Unigene: 33870 Mouse
Unigene: 79765 Zebrafish

ELP4,ELP4蛋白抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品图片	Protein: Hela lysate;  Primary: rabbit Anti-ELP4 (HZ-14574R) at 1:300;  Secondary: HRP conjugated Goat-Anti-rabbit IgG(HZ-0295G-HRP) at 1: 5000;  Predicted band size: 47 kD Observed band size: 47 kD