UGP2 polyclonal antibody
产品名称: UGP2 polyclonal antibody
英文名称: UGP2 polyclonal antibody
产品编号: PAB2609
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of UGP2.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human UGP2.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Ammonium sulfate precipitation
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:50-100)
Immunohistochemistry (1:10-50)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Large-scale mapping of human protein-protein interactions by mass spectrometry.
Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D.Mol Syst Biol. 2007;3:89. Epub 2007 Mar 13.
- 2.
- Expressed sequence tag analysis of human RPE/choroid for the NEIBank Project: over 6000 non-redundant transcripts, novel genes and splice variants.
Wistow G, Bernstein SL, Wyatt MK, Fariss RN, Behal A, Touchman JW, Bouffard G, Smith D, Peterson K.Mol Vis. 2002 Jun 15;8:205-20.
- 3.
- The importance of conserved residues in human liver UDPglucose pyrophosphorylase.
Chang HY, Peng HL, Chao YC, Duggleby RG.Eur J Biochem. 1996 Mar 1;236(2):723-8.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of UGP2 polyclonal antibody (Cat # PAB2609) in A2058 cell line lysates (35 ug/lane). UGP2 (arrow) was detected using the purified polyclonal antibody (1 : 60 dilution).
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human hepatocarcinomareacted with UGP2 polyclonal antibody (Cat # PAB2609), which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.
This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Entrez GeneID:
- 7360
- Protein Accession#:
- NP_006750;Q16851
- Gene Name:
- UGP2
- Gene Alias:
- UDPG,UDPGP2,UGPP2,pHC379
- Gene Description:
- UDP-glucose pyrophosphorylase 2
- Omim ID:
- 191760
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The enzyme encoded by this gene is an important intermediary in mammalian carbohydrate interconversions. It transfers a glucose moiety from glucose-1-phosphate to MgUTP and forms UDP-glucose and MgPPi. In liver and muscle tissue, UDP-glucose is a direct precursor of glycogen; in lactating mammary gland it is converted to UDP-galactose which is then converted to lactose. The eukaryotic enzyme has no significant sequence similarity to the prokaryotic enzyme. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- UDP-glucose diphosphorylase,UGPase 2,UTP--glucose-1-phosphate uridylyltransferase 2,UTP-glucose-1-phosphate uridyltransferase,uridyl diphosphate glucose pyrophosphorylase 2