FOXP2 polyclonal antibody
产品名称： FOXP2 polyclonal antibody
英文名称： FOXP2 polyclonal antibody
产品编号： PAB6067
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of FOXP2.
- Immunogen:
- A synthetic peptide corresponding to C-terminus of human FOXP2.
- Sequence:
- C-REIEEEPLSEDLE
- Host:
- Goat
- Theoretical MW (kDa):
- 79.9, 82.6, 70.1
- Reactivity:
- Human, Mouse
- Specificity:
- This antibody is expected to recognize all three reported isoforms (NP_055306.1, NP_683696.2, NP_683697.1).
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:32000)
Western Blot (0.5-1.5 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- A forkhead-domain gene is mutated in a severe speech and language disorder.
Lai CS, Fisher SE, Hurst JA, Vargha-Khadem F, Monaco AP.Nature. 2001 Oct 4;413(6855):519-23.
- Entrez GeneID:
- 93986
- Protein Accession#:
- NP_055306.1;NP_683696.2;NP_683697.1
- Gene Name:
- FOXP2
- Gene Alias:
- CAGH44,DKFZp686H1726,SPCH1,TNRC10
- Gene Description:
- forkhead box P2
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes an evolutionarily conserved transcription factor expressed in fetal and adult brain. This transcription factor is a member of the forkhead/winged-helix (FOX) family of transcription factors, and contains a FOX DNA-binding domain and a large polyglutamine tract. Members of the FOX family of transcription factors are regulators of embryogenesis. The product of this gene is thought to be required for proper development of speech and language regions of the brain during embryogenesis. Although a point mutation in this gene has been associated with the KE pedigree segregating developmental verbal dyspraxia, no association between mutations in this gene and another speech disorder, autism, has been found. Multiple alternative transcripts encoding different isoforms have been identified. [provided by RefSeq
- Other Designations:
- CAG repeat protein 44,OTTHUMP00000067772,forkhead/winged-helix transcription factor,speech and language disorder 1,trinucleotide repeat containing 10
- Related Disease
- Articulation Disorders
- Attention Deficit Disorder with Hyperactivity
- Autistic Disorder
- Cardiovascular Diseases
- Celiac Disease
- Cleft Lip
- Cleft Palate
- Diabetes Mellitus, Type 2
- Edema
- Genetic Predisposition to Disease
- Hallucinations
- Language Development Disorders
- Language Disorders
- Mental Disorders
- NARP
- Obesity
- Psychiatric Status Rating Scales
- Schizophrenia
- Schizophrenia