FITC标记的分泌模块化钙结合蛋白2/平滑肌相关蛋白2抗体-抗体-抗体-生物在线
上海沪震实业有限公司
FITC标记的分泌模块化钙结合蛋白2/平滑肌相关蛋白2抗体

FITC标记的分泌模块化钙结合蛋白2/平滑肌相关蛋白2抗体

商家询价

产品名称: FITC标记的分泌模块化钙结合蛋白2/平滑肌相关蛋白2抗体

英文名称: Anti-SMOC2/FITC

产品编号: HZ-7506R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围:

上海沪震实业有限公司
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 Rabbit Anti-SMOC2/FITC Conjugated antibody

FITC标记的分泌模块化钙结合蛋白2/平滑肌相关蛋白2抗体

 

英文名称 Anti-SMOC2/FITC
中文名称 FITC标记的分泌模块化钙结合蛋白2/平滑肌相关蛋白2抗体
别    名 Secreted modular calcium binding protein 2; SMAP 2; SMAP2; SMOC 2; Smooth muscle associated protein 2; SPARC related modular calcium binding 2; dJ421D16.1; MST117; MSTP117; bA270C4A.1; bA37D8.1; dJ421D16.1 (novel thyroglobulin type 1 repeat containing protein); MSTP140; SMOC2_HUMAN.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 心血管  细胞生物  信号转导  生长因子和激素  转录调节因子  血管内皮细胞  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, 
产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 47kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SMOC2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
SMOC 2 (Secreted modular calcium binding protein 2) is a secreted modular protein containing an EF hand calcium binding domain homologous to that in BM40. It consists of two thyroglobulin like domains, a follistatin like domain and a novel domain found only in the homologous SMOC 1. SMOC 1 and 2 form a separate group within the BM40 family. SMOC 2 is a glycoprotein with a calcium dependent conformation. SMOC 2 contains 2 EF hand calcium binding domains, 1 Kazal like domain and 2 thyroglobulin type I domains.

Function:
Promotes matrix assembly and cell adhesiveness. Can stimulate endothelial cell proliferation, migration, as well as angiogenesis. 

Subunit:
Binds various proteins from the extracellular matrix.

Subcellular Location:
Secreted, extracellular space, extracellular matrix, basement membrane.

DISEASE:
Defects in SMOC2 are the cause of dentin dysplasia typ1 (DTDP1) [MIM:125400]. A dental defect in which both primary and secondary dentitions are affected. The clinical crowns of both permanent and deciduous teeth are of normal shape, form and color in most cases, although they may be slightly opalescent and blue or brown. Teeth may be very mobile and exfoliate spontaneously because of inadequate root formation. On radiographs, the roots are short and may be more pointed than normal. Pulp chambers are usually absent except for a chevron-shaped remnant in the crown. Root canals are usually absent. 

Similarity:
Contains 2 EF-hand domains. 
Contains 1 Kazal-like domain. 
Contains 2 thyroglobulin type-1 domains. 

Database links:

Entrez Gene: 64094 Human

Entrez Gene: 64074 Mouse

Omim: 607223 Human

SwissProt: Q9H3U7 Human

SwissProt: Q8CD91 Mouse

Unigene: 487200 Human

Unigene: 30162 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications

SMOC 2(分泌型模块化钙结合蛋白2)是一种分泌型模块化蛋白,其包含与BM40同源的EF手钙结合结构域。它由两个甲状腺球蛋白样结构域,一个卵泡抑素样结构域和一个新的结构域仅在同源的SAMC 1中发现。SMOC 1和2在BM40家族中形成单独的组。SMOC 2是一种具有钙依赖构象的糖蛋白。SAMC 2包含2个EF手钙结合结构域,1 kAZAL样结构域和2个甲状腺球蛋白I型结构域。