SLC22A4 Pre-design Chimera RNAi
产品名称： SLC22A4 Pre-design Chimera RNAi
英文名称： SLC22A4 Pre-design Chimera RNAi
产品编号： H00006583-R01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- Specification
- Product Description:
- Homo sapiens solute carrier family 22 (organic cation transporter), member 4 (SLC22A4), mRNA.
- Reactivity:
- Human
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_003059
- Note:
- Position of the Chimera RNAi.
-
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 6583
- Gene Name:
- SLC22A4
- Gene Alias:
- MGC34546,MGC40524,OCTN1
- Gene Description:
- solute carrier family 22 (organic cation/ergothioneine transporter), member 4
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is an organic cation transporter and plasma integral membrane protein containing eleven putative transmembrane domains as well as a nucleotide-binding site motif. Transport by this protein is at least partially ATP-dependent. [provided by RefSeq
- Other Designations:
- integral membrane transport protein,organic cation transporter 4,solute carrier family 22 (organic cation transporter), member 4,solute carrier family 22 member 4
- Related Disease
- Anus Diseases
- Arthritis, Psoriatic
- Arthritis, Rheumatoid
- Asthma
- Autoimmune Diseases
- Bronchiolitis, Viral
- Cholangitis, Sclerosing
- Colitis, Ulcerative
- Colorectal Neoplasms
- Crohn Disease
- Crohn's disease
- Diabetes Mellitus, Type 1
- Disease Progression
- Disease Susceptibility
- Epilepsy
- Food Hypersensitivity
- Genetic Predisposition to Disease
- Growth Disorders
- Hypersensitivity, Immediate