FITC标记的9号染色体开放阅读框152抗体
产品名称: FITC标记的9号染色体开放阅读框152抗体
英文名称: Anti-C9orf152/FITC
产品编号: HZ-9497R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-C9orf152/FITC Conjugated antibody
FITC标记的9号染色体开放阅读框152抗体
产品编号 | bs-9497R-FITC |
英文名称 | Anti-C9orf152/FITC |
中文名称 | FITC标记的9号染色体开放阅读框152抗体 |
别 名 | Chromosome 9 open reading frame 152; Hypothetical protein LOC401546; Uncharacterized protein C9orf152; CI152_HUMAN. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 发育生物学 信号转导 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 26kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human C9orf152 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: C9orf152 is a 239 amino acid protein encoded by a gene that maps to human chromosome 9q31.3. Chromosome 9 consists of about 145 million bases, represents 4% of the human genome and encodes nearly 900 genes. Thought to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias. Database links: Entrez Gene: 401546 Human SwissProt: Q5JTZ5 Human Unigene: 125608 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
C9ORF 152是由人类染色体9q31.3的基因编码的239氨基酸蛋白质。9号染色体由约1亿4500万个碱基组成,占人类基因组的4%,编码近900个基因。认为在性别决定中起作用的是,9P末端的缺失会导致男性与女性性别逆转的发展,一个具有男性X、Y基因型的女性的表型。遗传性出血性毛细血管扩张症,其特征是由有害的血管缺陷,与编码EngGLN蛋白的染色体9基因有关。家族性失代偿也通过基因IKBKAP与9号染色体相关。值得注意的是,9号染色体包含最大的干扰素家族基因簇。染色体9与易位的22号染色体相关,导致BCR-ABL融合蛋白在白血病中的异常生成。