MSH2 polyclonal antibody
产品名称： MSH2 polyclonal antibody
英文名称： MSH2 polyclonal antibody
产品编号： PAB14663
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of MSH2.
- Immunogen:
- A synthetic peptide corresponding to amino acids 347-362 of human MSH2.
- Sequence:
- KQPLMDKNRIEERLNL
- Host:
- Rabbit
- Reactivity:
- Bovine, Dog, Frog, Human, Monkey, Mouse, Orangutan, Rat, Yeast
- Specificity:
- The amino acid sequence used as immunogen is 100% homologous in human, rat, dog, monkey orangutan, bovine and S. cerevisiae, and 93% in mouse and Xenopus.
- Form:
- Liquid
- Storage Buffer:
- In serum (50% glycerol, 0.025% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:100-1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer.
Fishel R, Lescoe MK, Rao MR, Copeland NG, Jenkins NA, Garber J, Kane M, Kolodner R.Cell. 1993 Dec 3;75(5):1027-38.
- Application Image
- ELISA
- Entrez GeneID:
- 4436
- Protein Accession#:
- NP_566804
- Gene Name:
- MSH2
- Gene Alias:
- COCA1,FCC1,HNPCC,HNPCC1,LCFS2
- Gene Description:
- mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. [provided by RefSeq
- Other Designations:
- mutS homolog 2
- Gene Pathway
- Related Disease
- Adenocarcinoma
- Adenoma
- Adenomatous Polyposis Coli
- Anticipation, Genetic
- Ataxia telangiectasia
- Brain Neoplasms
- Breast cancer
- Breast Neoplasms
- Carcinoma
- Carcinoma, Hepatocellular
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Papillary
- Carcinoma, Renal Cell
- Carcinoma, Squamous Cell
- Cell Transformation, Neoplastic
- Chromosomal Instability
- Chromosome Deletion
- Chronic Disease
- Colon cancer