GDNF (Human) Recombinant Protein-蛋白质/抗原/多肽-试剂-生物在线
亚诺法生技股份有限公司（Abnova)
GDNF (Human) Recombinant Protein

GDNF (Human) Recombinant Protein

商家询价

产品名称： GDNF (Human) Recombinant Protein

英文名称： GDNF (Human) Recombinant Protein

产品编号： P4394

产品价格： 0

产品产地： 台湾

品牌商标： Abnova

更新时间： null

使用范围： null

亚诺法生技股份有限公司（Abnova)
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  • Specification
  • Product Description:
  • Human GDNF (P39905) recombinant protein expressed in Escherichia coli.
  • Sequence:
  • MSPDKQMAVLPRRERNRQAAAANPENSRGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCDAAETTYDKILKNLSRNRRLVSDKVGQACCRPIAFDDDLSFLDDNLVYHILRKHSAKRCGCI
  • Theoretical MW (kDa):
  • 30.4
  • Form:
  • Lyophilized
  • Preparation Method:
  • Escherichia coli expression system
  • Endotoxin Level:
  • < 0.01 ng/ug or < 0.1 EU/ug
  • Activity:
  • The activity is determined by the dose-dependent proliferation of C6 cells. The expected ED50 for this effect is 1.7-2.6 ug/mL.
  • Storage Buffer:
  • Lyophilized from 10 mM sodium citrate, 100 mM NaCl, pH 4.0
  • Storage Instruction:
  • Store at -20°C on dry atmosphere.
    After reconstitution with sterilized water, store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Quality Control Testing:
  • 1 ug/lane in 4-20% Tris-Glycine gel Stained with Coomassie Blue

    QC Testing of P4394
    Lane 1: non-reducing conditions
    Lane 2: reducing conditions
  • Note:
  • Result of activity analysis

  • C6 cells were cultured with 0 to 10 ug/mL human GDNF. Cell proliferation was measured after 7 days and the linear portion of the curve was us used to calculate the ED50.
  • Applications
  • Functional Study
  • SDS-PAGE
  • Application Image
  • Functional Study
  • SDS-PAGE
  • Gene Information
  • Entrez GeneID:
  • 2668
  • Gene Name:
  • GDNF
  • Gene Alias:
  • ATF1,ATF2,HFB1-GDNF
  • Gene Description:
  • glial cell derived neurotrophic factor
  • Gene Summary:
  • This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. In addition to the transcript encoding GDNF, two additional alternative transcripts encoding distinct proteins, referred to as astrocyte-derived trophic factors, have also been described. Mutations in this gene may be associated with Hirschsprung disease. [provided by RefSeq
  • Other Designations:
  • astrocyte-derived trophic factor,glial cell line derived neurotrophic factor,glial derived neurotrophic factor

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