RPS6KB1 polyclonal antibody
产品名称： RPS6KB1 polyclonal antibody
英文名称： RPS6KB1 polyclonal antibody
产品编号： PAB18197
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of RPS6KB1.
- Immunogen:
- A synthetic peptide corresponding to residues surrounding T229 of human RPS6KB1.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Specificity:
- This antibody is specific to RPS6KB1.
- Form:
- Liquid
- Purification:
- Affinity purification
- Concentration:
- 1 mg/mL
- Storage Buffer:
- In PBS, 150mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:100)
Immunofluorescence (1:500-1:1000)
ELISA (1:40000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Cancer Res. 2002 Oct 15;62(20):5689-97.
Huang C, Li J, Ke Q, Leonard SS, Jiang BH, Zhong XS, Costa M, Castranova V, Shi X.Cancer Res. 2002 Oct 15;62(20):5689-97.
- 2.
- J Biol Chem. 2002 Jan 25;277(4):2525-33. Epub 2001 Nov 8.
Shah OJ, Iniguez-Lluhi JA, Romanelli A, Kimball SR, Jefferson LS.J Biol Chem. 2002 Jan 25;277(4):2525-33. Epub 2001 Nov 8.
- 3.
- Am J Physiol Endocrinol Metab. 2000 Jul;279(1):E74-82.
Shah OJ, Kimball SR, Jefferson LS.Am J Physiol Endocrinol Metab. 2000 Jul;279(1):E74-82.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of extracts from Jurkat cells, using RPS6KB1 polyclonal antibody (Cat # PAB18197).
Peptide "+" means "peptide blocking".
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Immunohistochemical analysis of paraffin-embedded human brain tissue using RPS6KB1 polyclonal antibody (Cat # PAB18197).
Peptide "+" means "peptide blocking".
- Entrez GeneID:
- 6198
- Protein Accession#:
- P23443
- Gene Name:
- RPS6KB1
- Gene Alias:
- PS6K,S6K,S6K1,STK14A,p70(S6K)-alpha,p70-S6K,p70-alpha
- Gene Description:
- ribosomal protein S6 kinase, 70kDa, polypeptide 1
- Omim ID:
- 608938
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized. [provided by RefSeq
- Other Designations:
- p70 S6 kinase, alpha 1,p70 S6 kinase, alpha 2,ribosomal protein S6 kinase, 70kD, polypeptide 1,serine/threonine kinase 14 alpha