DRD4 polyclonal antibody
产品名称： DRD4 polyclonal antibody
英文名称： DRD4 polyclonal antibody
产品编号： PAB7112
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of DRD4.
- Immunogen:
- A synthetic peptide corresponding to human DRD4.
- Sequence:
- C-PLRYNRQGGSRRQ
- Host:
- Goat
- Theoretical MW (kDa):
- 43.9
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:64000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Meta-analysis shows significant association between dopamine system genes and attention deficit hyperactivity disorder (ADHD).
Li D, Sham PC, Owen MJ, He L.Hum Mol Genet. 2006 Jul 15;15(14):2276-84. Epub 2006 Jun 14.
- Application Image
- ELISA
- Entrez GeneID:
- 1815
- Protein Accession#:
- NP_000788.2
- Gene Name:
- DRD4
- Gene Alias:
- D4DR
- Gene Description:
- dopamine receptor D4
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats. [provided by RefSeq
- Other Designations:
- D(2C) dopamine receptor,seven transmembrane helix receptor
- Gene Pathway
- Related Disease
- Alcoholic Intoxication
- Alcoholism
- Alzheimer Disease
- Alzheimer disease
- Amphetamine-Related Disorders
- Anorexia Nervosa
- Antisocial Personality Disorder
- Anxiety Disorders
- Anxiety, Separation
- Arousal
- Atrophy
- Attention
- Attention Deficit and Disruptive Behavior Disorders
- Attention Deficit Disorder with Hyperactivity
- Auditory Perceptual Disorders
- Autistic Disorder
- Behavior Therapy
- Bipolar Disorder
- Birth Weight