OLR1 monoclonal antibody (M08), clone 2C9
产品名称: OLR1 monoclonal antibody (M08), clone 2C9
英文名称: OLR1 monoclonal antibody (M08), clone 2C9
产品编号: H00004973-M08
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a full length recombinant OLR1.
- Immunogen:
- OLR1 (AAH22295, 1 a.a. ~ 273 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- MTFDDLKIQTVKDQPDEKSNGKKAKGLQFLYSPWWCLAAATLGVLCLGLVVTIMVLGMQLSQVSDLLTQEQANLTHQKKKLEGQISARQQAEEASQESENELKEMIETLARKLNEKSKEQMELHHQNLNLQETLKRVANCSAPCPQDWIWHGENCYLFSSGSFNWEKSQEKCLSLDAKLLKINSTADLDFIQQAISYSSFPFWMGLSRRNPSYPWLWEDGSPLMPHLFRVRGAVSQTYPSGTCAYIQRGAVYAENCILAAFSICQKKANLRAQ
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- MSDS:
- Download
- Applications
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged OLR1 is approximately 3ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 4973
- GeneBank Accession#:
- BC022295
- Protein Accession#:
- AAH22295
- Gene Name:
- OLR1
- Gene Alias:
- CLEC8A,LOX1,SCARE1
- Gene Description:
- oxidized low density lipoprotein (lectin-like) receptor 1
- Omim ID:
- 602601
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a receptor protein which belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternative transcript variants have been described but their full-length sequence has not been determined. [provided by RefSeq
- Other Designations:
- lectin-type oxidized LDL receptor 1,oxidised low density lipoprotein (lectin-like) receptor 1,scavenger receptor class E, member 1
- Gene Pathway
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Atherosclerosis
- Atherosclerosis
- Brain Ischemia
- Calcinosis
- Cardiovascular Diseases
- Cerebral Amyloid Angiopathy
- Cerebrovascular Accident
- Cerebrovascular Disorders
- Constriction, Pathologic
- Coronary Artery Disease
- Coronary Stenosis
- Diabetes Complications
- Diabetes Mellitus, Type 2
- Disease Progression
- Drug Toxicity
- Edema
- Genetic Predisposition to Disease