NR1H3/NR1H2 polyclonal antibody
产品名称： NR1H3/NR1H2 polyclonal antibody
英文名称： NR1H3/NR1H2 polyclonal antibody
产品编号： PAB12535
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of NR1H3/NR1H2.
- Immunogen:
- A synthetic peptide corresponding to amino acids 50-150 of human NR1H3/NR1H2.
- Host:
- Rabbit
- Reactivity:
- Chicken, Human, Mouse, Primates, Rat
- Specificity:
- This antibody is specific to LXR alpha and beta isoforms.
- Form:
- Liquid
- Storage Buffer:
- In Tris-glycine, 150 mM NaCl (0.05% sodium azide)
- Storage Instruction:
- Store at 4°C. Do not freeze.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Western Blot (0.5-2 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Suppression of 2,3-oxidosqualene cyclase by high fat diet contributes to liver X receptor-alpha-mediated improvement of hepatic lipid profile.
Dang H, Liu Y, Pang W, Li C, Wang N, Shyy JY, Zhu Y.J Biol Chem. 2009 Mar 6;284(10):6218-26. Epub 2009 Jan 1.
- 2.
- Atorvastatin decreases lipoprotein lipase and endothelial lipase expression in human THP-1 macrophages.
Qiu G, Hill JS.J Lipid Res. 2007 Oct;48(10):2112-22. Epub 2007 Jul 20.
- 3.
- NO-1886 upregulates ATP binding cassette transporter A1 and inhibits diet-induced atherosclerosis in Chinese Bama minipigs.
Zhang C, Yin W, Liao D, Huang L, Tang C, Tsutsumi K, Wang Z, Liu Y, Li Q, Hou H, Cai M, Xiao J.J Lipid Res. 2006 Sep;47(9):2055-63. Epub 2006 Jun 28.
- Entrez GeneID:
- 10062
- Gene Name:
- NR1H3
- Gene Alias:
- LXR-a,LXRA,RLD-1
- Gene Description:
- nuclear receptor subfamily 1, group H, member 3
- Omim ID:
- 602423
- Gene Ontology:
- Hyperlink
- Other Designations:
- liver X receptor alpha,liver X receptor, alpha,liver X receptor-alpha
- Entrez GeneID:
- 7376
- Gene Name:
- NR1H2
- Gene Alias:
- LXR-b,LXRB,NER,NER-I,RIP15,UNR
- Gene Description:
- nuclear receptor subfamily 1, group H, member 2
- Omim ID:
- 600380
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The LX receptors (LXRs) were originally identified as orphan members of the nuclear receptor superfamily because their ligands were unknown. Like other receptors in the family, LXRs heterodimerize with retinoid X receptor (see MIM 180245) and bind to specific response elements (LXREs) characterized by direct repeats separated by 4 nucleotides. Two genes, alpha (LXRA, MIM 602423) and beta, are known to encode LXR proteins (Song et al., 1995 [PubMed 7625741]).[supplied by OMIM
- Other Designations:
- LX receptor beta,liver X receptor beta,liver X receptor-beta,nuclear orphan receptor LXR-beta,oxysterols receptor LXR-beta,steroid hormone-nuclear receptor NER,ubiquitously-expressed nuclear receptor