TYMS monoclonal antibody, clone TS 106
产品名称: TYMS monoclonal antibody, clone TS 106
英文名称: TYMS monoclonal antibody, clone TS 106
产品编号: MAB3411
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against recombinant TYMS.
- Immunogen:
- Recombinant protein corresponding to human TYMS.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Isotype:
- IgG1, kappa
- Storage Buffer:
- In 10 mM PBS, pH 7.4 (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. Do not freeze.
- Recommend Usage:
- Immunoprecipitation (2 ug/mg protein lysate)
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 7298
- Gene Name:
- TYMS
- Gene Alias:
- HsT422,MGC88736,TMS,TS,TSase
- Gene Description:
- thymidylate synthetase
- Omim ID:
- 188350
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase. [provided by RefSeq
- Other Designations:
- Thymidylate synthase
- Related Disease
- Abortion, Habitual
- Abortion, Spontaneous
- Acute Disease
- Adenocarcinoma
- Adenoma
- Adenomatous Polyps
- Aortic Aneurysm, Abdominal
- Arthritis, Reactive
- Arthritis, Rheumatoid
- Atherosclerosis
- Barrett Esophagus
- Behcet Syndrome
- Bile Duct Neoplasms
- Bone Neoplasms
- Brain Ischemia
- Breast cancer
- Breast Neoplasms
- Carcinoma
- Carcinoma, Ductal, Breast