HDAC11 polyclonal antibody
产品名称： HDAC11 polyclonal antibody
英文名称： HDAC11 polyclonal antibody
产品编号： PAB2342
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of HDAC11.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human HDAC11.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors.
Bradbury CA, Khanim FL, Hayden R, Bunce CM, White DA, Drayson MT, Craddock C, Turner BM.Leukemia. 2005 Oct;19(10):1751-9.
- 2.
- Chromosomal organization and localization of the novel class IV human histone deacetylase 11 gene.
Voelter-Mahlknecht S, Ho AD, Mahlknecht U.Int J Mol Med. 2005 Oct;16(4):589-98.
- 3.
- Molecular evolution of the histone deacetylase family: functional implications of phylogenetic analysis.
Gregoretti IV, Lee YM, Goodson HV.J Mol Biol. 2004 Apr 16;338(1):17-31.
- Applications
- Western Blot (Tissue lysate)
- Western blot analysis of HDAC11 polyclonal antibody (Cat # PAB2342) in mouse brain tissue lysate. HDAC11 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with the HDAC11 polyclonal antibody (Cat # PAB2342) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma.
- Entrez GeneID:
- 79885
- Protein Accession#:
- Q96DB2
- Gene Name:
- HDAC11
- Gene Alias:
- FLJ22237
- Gene Description:
- histone deacetylase 11
- Omim ID:
- 607226
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a class IV histone deacetylase. The encoded protein is localized to the nucleus and may be involved in regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants
- Other Designations:
- -