Calpain 12,钙激活蛋白酶12抗体

产品编号HZ-6798R
英文名称Calpain 12
中文名称钙激活蛋白酶12抗体
别 名Calpain12; Calpain-12; CAPN 12; CAPN12; EC 3.4.22.; MGC20576; CAN12_HUMAN.
说 明 书0.1ml 0.2ml
研究领域细胞生物 信号转导 细胞凋亡
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Dog, Pig, Cow,
Calpain 12,钙激活蛋白酶12抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量81kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human Calpain 12
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Calpain 12,钙激活蛋白酶12抗体PubMedPubMed
产品介绍background:
Calpains are a family of cytosolic calcium activated cysteine proteases involved in a variety of cellular processes including apoptosis, cell division, modulation of integrin and cytoskeletal interactions, and synaptic plasticity. Calpain 12 was first described in the mouse, most strongly in the skin, and maps to mouse chromosome 7. Isoforms differ in the carboxyterminal ends, ending with aberrant domain III and lacking domain IV. Domains in the large subunit include the amino terminal domain I, the proteinase domain II, domain III, and the EF hand domain IV, making Calpain 12 most similar to calpains 1 and 2.

Function:
Calcium-regulated non-lysosomal thiol-protease (By similarity).

Similarity:
Belongs to the peptidase C2 family.
Contains 1 calpain catalytic domain.
Contains 1 EF-hand domain.

Gene ID:
147968

Calpain 12,钙激活蛋白酶12抗体Database links:
Entrez Gene: 147968 Human
Entrez Gene: 60594 Mouse
Entrez Gene: 308476 Rat
Omim: 608839 Human
SwissProt: Q6ZSI9 Human
SwissProt: Q9ER56 Mouse
Unigene: 731775 Human
Unigene: 476990 Mouse
Unigene: 219171 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.