FITC标记的LARP7蛋白抗体-抗体-抗体-生物在线
上海沪震实业有限公司
FITC标记的LARP7蛋白抗体

FITC标记的LARP7蛋白抗体

商家询价

产品名称: FITC标记的LARP7蛋白抗体

英文名称: Anti-LARP7/FITC

产品编号: HZ-17106R-FITC

产品价格: null

产品产地: 中国/上海

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: ICC=1:50-200 IF=1:50-200

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 Rabbit Anti-LARP7/FITC Conjugated antibody

FITC标记的LARP7蛋白抗体

 

英文名称 Anti-LARP7/FITC
中文名称 FITC标记的LARP7蛋白抗体
别    名 DKFZp564K112; HDCMA18P; La related protein 7; La ribonucleoprotein domain family member 7; La ribonucleoprotein domain family member 7; La-related protein 7; LARP 7; larp7; LARP7_HUMAN; MGC104360; P TEFb interaction protein for 7SK stability; P-TEFb-interaction protein for 7SK stability; PIP7S.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  转录调节因子  结合蛋白  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 67kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LARP7
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
This gene encodes a protein which is found in the 7SK snRNP (small nuclear ribonucleoprotein). This snRNP complex inhibits a cyclin-dependent kinase, positive transcription elongation factor b, which is required for paused RNA polymerase II at a promoter to begin transcription elongation. A pseudogene of this gene is located on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012]

Function:
Negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b (P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.

Subcellular Location:
Nucleus > nucleoplasm.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Contains 1 HTH La-type RNA-binding domain.
Contains 1 RRM (RNA recognition motif) domain.

Database links:

Entrez Gene: 51574 Human

Entrez Gene: 28036 Mouse

Entrez Gene: 686883 Rat

Omim: 612026 Human

SwissProt: Q4G0J3 Human

SwissProt: Q05CL8 Mouse

SwissProt: Q5XI01 Rat

Unigene: 713663 Human

Unigene: 291032 Mouse

Unigene: 168323 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   

该基因编码在7SK SNRNP(小核糖核蛋白)中发现的一种蛋白质。该snRNP复合物抑制细胞周期素依赖性激酶,即阳性转录延长因子b,它是启动子处暂停的RNA聚合酶II开始转录延长所必需的。该基因的假基因位于3号染色体上。选择性剪接导致多个转录变体。[ RefSeq,2012年5月提供]