ATP7A/CENXp FISH Probe
产品名称: ATP7A/CENXp FISH Probe
英文名称: ATP7A/CENXp FISH Probe
产品编号: FG0056
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
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- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Labeled FISH probes for identification of gene amplification using Fluoresecent In Situ Hybridization Technique. (Technology)
- Storage Instruction:
- Store at 4°C in the dark.
- Quality Control Testing:
- Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
- Supplied Product:
- DAPI Counterstain (1500 ng/mL ) 250 uL
- Note:
- Hybridization position of the probes on the chromosome:
-
- Probe 1:
Size:
Fluorophore:
Location: - ATP7A
Approximately 350kb
Texas Red
Xq21.1
- Probe 2:
Size:
Fluorophore:
Location: - CENXp
Approximately 550kb
FITC
Xp11.22
- Probe Gap:
- The gap between two probes is approximately 27,500 kb.
- Origin:
- Human
- Source:
- Genomic DNA
- Regulation Status:
- For research use only (RUO)
- Applications
- Fluorescent In Situ Hybridization (Cell)
- Protocol Download
- Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge this image
- Human ovary cancer (FFPE) stained with ATP7A/CENXp FISH Probe. Human ovary cancer showed no ATP7A gene amplification.
- Protocol Download
- Application Image
- Fluorescent In Situ Hybridization (Cell)
- Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Entrez GeneID:
- 538
- Gene Name:
- ATP7A
- Gene Alias:
- FLJ17790,MK,MNK
- Gene Description:
- ATPase, Cu++ transporting, alpha polypeptide
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a transmembrane protein that functions in copper transport across membranes. The protein localizes to the trans-Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. The protein relocalizes to the plasma membrane under conditions of elevated extracellular copper and functions in the efflux of copper from cells. Mutations in this gene result in Menkes disease, X-linked cutis laxa, and occipital horn syndrome. [provided by RefSeq
- Other Designations:
- Cu++-transporting P-type ATPase,Menkes disease-associated protein,Menkes syndrome,OTTHUMP00000023593,OTTHUMP00000062077,copper pump 1,copper-transporting ATPase 1