ITGAM monoclonal antibody (M07), clone 4E10
产品名称: ITGAM monoclonal antibody (M07), clone 4E10
英文名称: ITGAM monoclonal antibody (M07), clone 4E10
产品编号: H00003684-M07
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant ITGAM.
- Immunogen:
- ITGAM (NP_000623, 111 a.a. ~ 220 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- QTCSENTYVKGLCFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLKKSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQ
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG1 Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- MSDS:
- Download
- Applications
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged ITGAM is 1 ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 3684
- GeneBank Accession#:
- NM_000632
- Protein Accession#:
- NP_000623
- Gene Name:
- ITGAM
- Gene Alias:
- CD11B,CR3A,MAC-1,MAC1A,MGC117044,MO1A,SLEB6
- Gene Description:
- integrin, alpha M (complement component 3 receptor 3 subunit)
- Omim ID:
- 120980
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- antigen CD11b (p170),complement component receptor 3, alpha,integrin alpha M,macrophage antigen alpha polypeptide,neutrophil adherence receptor alpha-M subunit
- Related Disease
- Autoimmune Diseases
- Cardiovascular Diseases
- Crohn's disease
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Disease Susceptibility
- Edema
- Genetic Predisposition to Disease
- Helicobacter Infections
- Lupus Erythematosus, Discoid
- Lupus Erythematosus, Systemic
- Lupus Nephritis
- Macular Degeneration
- Nephritis
- Stomach Ulcer