FITC标记的1号染色体开放阅读框31抗体
产品名称： FITC标记的1号染色体开放阅读框31抗体
英文名称： Anti-C1orf31/FITC
产品编号： HZ-9785R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-C1orf31/FITC Conjugated antibody
FITC标记的1号染色体开放阅读框31抗体
| 产品编号 | bs-9785R-FITC |
| 英文名称 | Anti-C1orf31/FITC |
| 中文名称 | FITC标记的1号染色体开放阅读框31抗体 |
| 别 名 | C1orf31; CA031_HUMAN; Chromosome 1 open reading frame 31; Hypothetical protein LOC388753; RP5-827C21.3; Uncharacterized protein C1orf31. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 干细胞 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 14kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human C1orf31 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water. C1orf31 is a 125 amino acid mitochondrial protein that belongs to the cytochrome c oxidase subunit 6B family. There are three isoforms of C1orf31 that are produced as a result of alternative splicing events. The gene encoding C1orf31 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. Subunit: Interacts with COA1. Subcellular Location: Mitochondrion. Similarity: Belongs to the cytochrome c oxidase subunit 6B family. Database links: Entrez Gene: 388753 Human Omim: 614772 Human SwissProt: Q5JTJ3 Human Unigene: 23198 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
细胞色素C氧化酶（COX）家族的蛋白质作为呼吸链中的最终电子供体，以驱动穿过线粒体内膜的质子梯度，最终导致水的产生。C1OF31是属于细胞色素C氧化酶亚基6B家族的125氨基酸线粒体蛋白。作为替代剪接事件的结果，产生了三种C1ORF 31的异构体。编码C1ORF的基因编码到人类1号染色体上，最大的人类染色体跨越2亿6000万个碱基对，占人类基因组的8%。在1号染色体上有大约3000个基因，并且考虑到大量的基因，也有大量的与染色体1相关的疾病。值得注意的是，罕见的衰老性疾病Hutchinson Gilford早老症与LMNA基因编码，lamin A.基因在缺陷时编码，LMNA基因产物可在细胞核中积聚并引起特征性核泡。迅速增强衰老的机制尚不清楚，是一个继续探索的话题。