FITC标记的泛素样蛋白SUMO2激活酶抗体
产品名称： FITC标记的泛素样蛋白SUMO2激活酶抗体
英文名称： Anti-SAE2 / UBA2/FITC
产品编号： HZ-19366R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-SAE2 / UBA2/FITC Conjugated antibody
FITC标记的泛素样蛋白SUMO2激活酶抗体
| 英文名称 | Anti-SAE2 / UBA2/FITC |
| 中文名称 | FITC标记的泛素样蛋白SUMO2激活酶抗体 |
| 别 名 | Anthracycline associated resistance ARX; Anthracycline-associated resistance ARX; ARX; FLJ13058; HRIHFB2115; SAE 2; SAE2; SAE2_HUMAN; SUMO 1 activating enzyme subunit 2; SUMO activating enzyme subunit 2; SUMO-activating enzyme subunit 2; UBA2; UBA2 ubiquitin activating enzyme E1 homolog; Ubiquitin like 1 activating enzyme E1B; Ubiquitin like modifier activating enzyme 2; Ubiquitin-like 1-activating enzyme E1B; UBLE1B. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 泛素 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Horse, Rabbit, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 71kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SAE2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 (MIM 613294) and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010] Function: The heterodimer acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Subcellular Location: Nucleus. Similarity: Belongs to the ubiquitin-activating E1 family. Database links: Entrez Gene: 10054 Human Entrez Gene: 50995 Mouse Entrez Gene: 308508 Rat Entrez Gene: 406672 Zebrafish Omim: 613295 Human SwissProt: Q9UBT2 Human SwissProt: Q9Z1F9 Mouse SwissProt: Q7SXG4 Zebrafish Unigene: 631580 Human Unigene: 27560 Mouse Unigene: 198150 Rat Unigene: 78013 Zebrafish Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
posttranslational修改蛋白质by the加of the小蛋白（see sumo1相扑；MIM 601912）、金修饰，对蛋白质结构和细胞内定位。sae1（MIM 613294）和uba2形成heterodimer that功能有相扑活化酶蛋白（for the修饰of大隈等人，1999 9920803 ] [ PubMed）。[ 3 ] supplied by OMIM，2010