FITC标记的钾离子通道多聚体结构域蛋白15抗体
产品名称： FITC标记的钾离子通道多聚体结构域蛋白15抗体
英文名称： Anti-KCTD15/FITC
产品编号： HZ-16927R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-KCTD15/FITC Conjugated antibody
FITC标记的钾离子通道多聚体结构域蛋白15抗体
| 英文名称 | Anti-KCTD15/FITC |
| 中文名称 | FITC标记的钾离子通道多聚体结构域蛋白15抗体 |
| 别 名 | TB/POZ domain containing protein KCTD15; BTB/POZ domain-containing protein kctd15; KCD15_HUMAN; KCTD 15; kctd15; MGC25497; MGC2628; Potassium channel tetramerisation domain containing 15. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 神经生物学 通道蛋白 细胞膜受体 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Horse, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 32kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KCTD15 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: KCTD15 is a 283 amino acid protein that contains one BTB (POZ) domain and exists as two alternatively spliced isoforms. The gene that encodes KCTD15 consists of approximately 18,918 bases and maps to human chromosome 19q13.11. Consisting of around 63 million bases with more than 1,400 genes, chromosome 19 makes up over 2% of the human genome. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG families, and Fc?receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene BCL3. Similarity: Contains 1 BTB (POZ) domain. Database links: Entrez Gene: 79047 Human Entrez Gene: 512578 Cow Entrez Gene: 233107 Mouse Entrez Gene: 499129 Rat SwissProt: Q0VD00 Cow SwissProt: Human SwissProt: Q8K0E1 Mouse Unigene: 221873 Human Unigene: 606506 Human Unigene: 214380 Mouse Unigene: 87232 Zebrafish Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
KCTD15是包含一个BTB（POZ）结构域的283个氨基酸的蛋白质，作为两个交替剪接的异构体存在。编码KCTD15的基因由大约18918个碱基组成，并映射到人类染色体19q1311。由大约6300万个碱基和1400个以上的基因组成，19号染色体构成了人类基因组的2%以上。它是许多免疫球蛋白超家族成员的遗传家园，包括杀伤细胞和白细胞Ig样受体、许多ICAM、CEACAM和PSG家族以及Fc?受体。眼睛颜色和头发颜色的关键基因也映射到19号染色体上。Peutz-Jeghers综合征，脊髓小脑性共济失调6型，中风病CADASIL，高胆固醇血症和胰岛素依赖型糖尿病都与染色体19有关。在一些淋巴增生性疾病中可以看到19号染色体和14号染色体的易位，典型地涉及原癌基因BCL3。